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Michael F Michelis

Michael F Michelis

Lenox Hill Hospital, USA

Title: Argnine Vasopressin: What else does it do?

Biography

Biography: Michael F Michelis

Abstract

The pressor and antidiuretic actions of arginine vasopressin (AVP) have been well documented. It is also important to focus on less widely appreciated actions of AVP. In addition to effects on hemostasis, pain, aging, social behavior and cognition, AVP has important relationships to bone metabolism and a variety of metabolic systems which involve changes that have significant effects on nephrologic outcomes. These include involvement with the hypothalamic-pituitary-axis, inflammatory responses, cell proliferation and reaction to urinary infection, as well as components of the metabolic syndrome such as diabetes mellitus, lipid metabolism and hypertension. Finally, possible direct effects of AVP on the progression of chronic kidney disease will be considered.

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