Nephrology & Therapeutics

Biography

Biography: Cosmin Alecu

Abstract

Caribbean stroke patients are younger and their risk factors are different from those of European and North American patients, particularly in young. The analysis of a prospective study of consecutive patients with a first hemispheric stroke admitted in Pointe-à-Pitre (Guadeloupe, French West Indies) between December 2010 and February 2011 revealed us that chronic kidney disease is very frequent, 23.6% of chronic renal failure. The study included 78 patients (33 women), 24.4% with haemorrhagic stroke. The mean age was 62.1 ±17.7 years, 70.5% of patients had hypertension, 29.4% a diabetes. A common origin of stroke and kidney disease by microangiopathy can be suggested by the high rate of hypertension and diabetes. Nevertheless, stroke aetiologies (TOAST classification), were cardio-embolism (19.3%), atherosclerosis (61.4%), lacunar stroke (1.8%), other known (3.5%) and unknown or indeterminate aetiologies (14%). Chronic renal failure has significant influence on functional state one year later (p=0.03) and probably influences the post stroke death (p=0.07 in our population). We discussed in this presentation, enclosing literature data and results of our study, the kidney disease and neurovascular disease association.