Apeksha Niraula
B.P Koirala Institute of Health Sciences, India
Title: Cystatin-c as a marker for renal impairment in preeclampsia
Biography
Biography: Apeksha Niraula
Abstract
Background:
Preeclampsia (PE); a multisystem disorder of unknown etiology is characterized by development of hypertension to the extent of 140/90 mm Hg or more with proteinuria after the 20th week in a previously normotensive and non-proteinuric woman. This study was done to compare and evaluate the diagnostic efficiency of serum Cystatin-C, Creatinine and Uric Acid levels in PE and Normal pregnant women.
Materials and Methods:
This is a hospital based comparative cross-sectional study conducted in BPKIHS. One hundred and two study participants who provided the written consent were enrolled; of which fifty one participants were diagnosed cases of PE and fifty one served as Control. Serum Cystatin-C was done by Immunoturbidimetry method in Accent 200 Autoanalyser. Creatinine and Uric Acid was done by Jaffe’s and Uricase method in cobas c311 Autoanalyser respectively. ROC curve was used to evaluate the diagnostic efficiency of Cystatin-C in PE. p value < 0.05 was considered to be significant.