Michael D Wagener
Stellar Biomolecular Research (SBR) and FCTI Germany
Title: The role of intravenous phospholipds as a membrane therapeutic - a complementary treatment approach of CKD
Biography
Biography: Michael D Wagener
Abstract
Phosphatidylcholine is a phospholipid that is one of the main components of lecithin. Lecithin is found in all cell membranes and plays a major role in maintaining the fluidity of the cell by affecting what enters and leaves the cell through the cell membrane. Given as infusion, PC might improve many conditions, among them kidney function and overall energy. Clinical studies have been performed in glomerulonephritis, where a reduction of edema could be observed. Also in renal insufficiency patients showed an increase in creatinine, urine volume and renal clearance when receiving PC intravenously. Overall patients suffering from fatigue from various causes (e.g. chronic kidney disease) were benefiting from phosphatidylcholine infusions. Standard toxicological assessments indicate no significant acute or chronic toxicity from PC, as well as no mutagenicity and no teratogenicity.