Nephrology & Renal Care

Systemic lupus erythematosus (SLE) is an autoimmune systemic disease that is more common in women of child bearing age. Although the impact of pregnancy on SLE activity has been debated in the literature, majority of studies have noted increased SLE activity during pregnancy, causing peri-partum complications like pre-eclampsia, pre-term labour and stillbirth. Our case is a 31 year old woman who suffered pre-eclampsia during her pregnancy presenting one month later with haemolytic anaemia, decompensated cardiomyopathy with serositis and  acute renal impairment. She was diagnosed with systemic lupus erythematosis with Lupus Nephritis and started on immunosuppressive therapy with Steroids and Mycophenolate Mofetil. This case highlights the importance of understanding the heterogeneous nature of SLE presentation with multiple organ involvement and the impact on SLE activity on pregnancy and its outcomes.