Diabetic Nephropathy

Diabetic's nephropathy Diabetic nephropathy also known as Kimmelstiel–Wilson syndrome, or nodular diabetic glomerulosclerosisand intercapillary glomerulonephritis, is a progressive kidney disease caused by angiopathy of capillaries in the kidney glomeruli. It is characterized by nephrotic syndrome and diffuse glomerulosclerosis. It is due to longstanding diabetes mellitus, and is a prime indication for dialysis in many developed countries. It is classified as a small blood vessel complication of diabetes. Clinically, diabetic nephropathy is characterized by a progressive increase in proteinuria and decline in GFR,Hypertension, and a high risk of cardiovascular morbidity and mortality. Diabetes has become the primary cause of End-stage renal disease (ESRD) in the United States, and the incidence of type 2 diabetes mellitus continues to grow in the United States and worldwide as described in Nephritis conferences.

Approximately 44% of new patients entering dialysis in the United States are diabetics. Early diagnosis of diabetes and early intervention are critical in preventing the normal progression to renal failure seen in many type 1 and a significant percentage of type 2 diabetics. Approximately 20.8 million people, or 7.0% of the population in the United States, are estimated to have diabetes, with a growing incidence. Roughly one third of this population, 6.2 million, is estimated to be undiagnosed with type 2 diabetes. The prevalence of diabetes is higher in certain racial and ethnic groups, affecting approximately 13% of African Americans, 9.5% of Hispanics, and 15% of Native Americans, primarily with type 2 diabetes.1, 2 approximately 20% to 30% of all diabetics will develop evidence of nephropathy, although a higher percentage of type 1 patients progress to ESRD.

  • Hypertension, CKD and Diabetes
  • Hypertension- cause of renal diseases in diabetics
  • High blood pressure
  • Angiotensin receptor blockers
  • Enzyme inhibitors
  • High cholesterol

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Diabetic Nephropathy Conference Speakers

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