Nephrology & Renal Care

Chronic Kidney Disease

The term “Chronic kidney disease” means lasting damage to the kidneys that can get worse over time. If the damage is very bad, your kidneys may stop working. This is called Kidney failure, or End-stage renal disease (ESRD). CKD is rarely reversible and leads to progressive decline in renal function. Reduction in the renal mass leads to Hypertrophy of the remaining nephrons with hyper filtration and the GFR in these nephrons is transiently at supra-normal levels. The two main causes of chronic kidney disease are diabetes and high blood pressure, which are responsible for up to two-thirds of the cases. Severity of the condition may lead to hematologic & neurologic complications. CKD usually gets worse slowly, and symptoms may not appear until your kidneys are badly damaged. The common complications of CKD include anaemia, bone disease, heart disease, high potassium, high calcium and fluid build-up. The symptoms and treatment differs with the stage of the diseased condition. Primary treatment includes medication and secondary treatment in the worsen stage involves dialysis and transplantation