Nephrology & Therapeutics

Nephrotoxicity and Drug-induced Kidney Injury

Nephrotoxicity and Drug-induced Kidney Injury occur when medications or toxins cause damage to the kidneys. Common culprits include nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, and certain chemotherapies, which can lead to acute kidney injury (AKI) or chronic kidney damage. Nephrotoxicity may manifest as electrolyte imbalances, reduced kidney function, or acute renal failure. Early detection through monitoring kidney function and adjusting drug doses is key in preventing long-term damage. Research is focused on developing safer drugs and improving early biomarkers to better manage drug-induced kidney injuries and mitigate adverse effects.